Patient-specific models of cardiac biomechanics

Patient-specific isogeometric analysis for vascular biomechanics

Isogeometric Analysis (IGA) has recently emerged as a cost-effective alternative to classic isoparametric Finite Element Analysis. In this work a novel computational framework is proposed in order to get IGA-suitable geometries to simulate different vascular minimally-invasive procedures. The preliminary results show the capability of the framework to import in a straightforward way patient-spe...

Patient-specific Modeling of Cardiac Biomechanics in Repaired Tetralogy of Fallot

Towards Patient Specific Models of Cardiac Mechanics: A Sensitivity Study

In the design of patient specific mathematical models of cardiac mechanics, the lack of patient specific input data leads to default settings of various model parameters. To estimate the potential errors thus introduced, we evaluated changes in predicted mechanics in a model of the left ventricle (LV) induced by changes in geometry, fiber orientation, heterogeneity of passive material behavior ...

Cardiac Biomechanics

Andrew D. McCulloch University of California 54.

Cell-Specific Cardiac Electrophysiology Models

The traditional cardiac model-building paradigm involves constructing a composite model using data collected from many cells. Equations are derived for each relevant cellular component (e.g., ion channel, exchanger) independently. After the equations for all components are combined to form the composite model, a subset of parameters is tuned, often arbitrarily and by hand, until the model outpu...